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Nuclear localization of Newcastle disease virus matrix protein promotes virus replication by affecting viral RNA synthesis and transcription and inhibiting host cell transcription

Nuclear localization of paramyxovirus proteins is crucial for virus life cycle, including the regulation of viral replication and the evasion of host immunity. We previously showed that a recombinant Newcastle disease virus (NDV) with nuclear localization signal mutation in the matrix (M) protein re...

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Detalles Bibliográficos
Autores principales: Duan, Zhiqiang, Deng, Shanshan, Ji, Xinqin, Zhao, Jiafu, Yuan, Chao, Gao, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425612/
https://www.ncbi.nlm.nih.gov/pubmed/30894203
http://dx.doi.org/10.1186/s13567-019-0640-4