Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

BACKGROUND: Large-scale genetic screening using CRISPR-Cas9 technology has emerged as a powerful approach to uncover and validate gene functions. The ability to control the timing of genetic perturbation during CRISPR screens will facilitate precise dissection of dynamic and complex biological proce...

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Detalles Bibliográficos
Autores principales: Sun, Ning, Petiwala, Sakina, Wang, Rui, Lu, Charles, Hu, Mufeng, Ghosh, Sujana, Hao, Yan, Miller, Christopher P., Chung, Namjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425629/
https://www.ncbi.nlm.nih.gov/pubmed/30890156
http://dx.doi.org/10.1186/s12864-019-5601-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425629/
https://www.ncbi.nlm.nih.gov/pubmed/30890156
http://dx.doi.org/10.1186/s12864-019-5601-9

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