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Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening
BACKGROUND: Large-scale genetic screening using CRISPR-Cas9 technology has emerged as a powerful approach to uncover and validate gene functions. The ability to control the timing of genetic perturbation during CRISPR screens will facilitate precise dissection of dynamic and complex biological proce...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425629/ https://www.ncbi.nlm.nih.gov/pubmed/30890156 http://dx.doi.org/10.1186/s12864-019-5601-9 |