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Development of Effective Therapeutics Targeting HER3 for Cancer Treatment

HER3 is the third member of the human epidermal growth factor receptor (HER/EGFR) family, and unlike its other family members, is unique due to its minimal intrinsic kinase activity. As a result, HER3 has to interact with another receptor tyrosine kinase (RTK), such as EGFR or HER2, in order to acti...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolong, Liu, Shuang, Lyu, Hui, Riker, Adam I., Zhang, Yamin, Liu, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425631/
https://www.ncbi.nlm.nih.gov/pubmed/30930695
http://dx.doi.org/10.1186/s12575-019-0093-1