Cargando…
Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are common
BACKGROUND: Despite the tremendous therapeutic advances that have stemmed from somatic oncogenetics, survival of some cancers has not improved in 50 years. Osteosarcoma still has a 5-year survival rate of 66%. We propose the natural canine osteosarcoma model can change that: it is extremely similar...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425649/ https://www.ncbi.nlm.nih.gov/pubmed/30890123 http://dx.doi.org/10.1186/s12864-019-5531-6 |