Cargando…

Recombinant RGD-disintegrin DisBa-01 blocks integrin α(v)β(3) and impairs VEGF signaling in endothelial cells

BACKGROUND: Integrins mediate cell adhesion, migration, and survival by connecting the intracellular machinery with the surrounding extracellular matrix. Previous studies demonstrated the interaction between α(v)β(3) integrin and VEGF type 2 receptor (VEGFR2) in VEGF-induced angiogenesis. DisBa-01,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Danilucci, Taís M., Santos, Patty K., Pachane, Bianca C., Pisani, Graziéle F. D., Lino, Rafael L. B., Casali, Bruna C., Altei, Wanessa F., Selistre-de-Araujo, Heloisa S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425665/ https://www.ncbi.nlm.nih.gov/pubmed/30894182 http://dx.doi.org/10.1186/s12964-019-0339-1

Ejemplares similares

Tumor heterogeneity and the dilemma of antioxidant therapies in cancer
por: Selistre-de-Araujo, Heloisa Sobreiro, et al.
Publicado: (2022)

Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles
por: Altei, Wanessa F., et al.
Publicado: (2020)

The Effects of αvβ3 Integrin Blockage in Breast Tumor and Endothelial Cells under Hypoxia In Vitro
por: Casali, Bruna C., et al.
Publicado: (2022)

Metastasis inhibition in breast cancer by targeting cancer cell extravasation
por: Cominetti, Márcia R, et al.
Publicado: (2019)

Snake Venom Disintegrins and Cell Migration
por: Selistre-de-Araujo, Heloisa S., et al.
Publicado: (2010)

Small Extracellular Vesicles from Hypoxic Triple-Negative Breast Cancer Cells Induce Oxygen-Dependent Cell Invasion
por: Pachane, Bianca Cruz, et al.
Publicado: (2022)

Inhibition of α(v)β(3) integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC)
por: Montenegro, Cyntia F., et al.
Publicado: (2017)

Disruptive behavior scale for adolescents (DISBA): development and psychometric properties
por: Karimy, Mahmood, et al.
Publicado: (2018)

Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom
por: Oliveira, Isadora Sousa de, et al.
Publicado: (2018)

Summary of the Structure Function Session at Dis01
por: Long, Kenneth, et al.
Publicado: (2001)

KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain
por: Hussein, Hosni A. M., et al.
Publicado: (2016)

Disintegrins from Hematophagous Sources
por: Assumpcao, Teresa C. F., et al.
Publicado: (2012)

Alternagin-C (ALT-C), a Disintegrin-Like Cys-Rich Protein Isolated from the Venom of the Snake Rhinocerophis alternatus, Stimulates Angiogenesis and Antioxidant Defenses in the Liver of Freshwater Fish, Hoplias malabaricus
por: Monteiro, Diana Amaral, et al.
Publicado: (2017)

Recombinant disintegrin (r-Cam-dis) from Crotalus adamanteus inhibits adhesion of human pancreatic cancer cell lines to laminin-1 and vitronectin
por: Suntravat, Montamas, et al.
Publicado: (2015)

Recombinant and Chimeric Disintegrins in Preclinical Research
por: David, Victor, et al.
Publicado: (2018)

Biological control of potato common scab by Bacillus amyloliquefaciens Ba01
por: Lin, Chih, et al.
Publicado: (2018)

ADAM-15 Disintegrin-Like Domain Structure and Function
por: Lu, Dong, et al.
Publicado: (2010)

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family
por: Kelwick, Richard, et al.
Publicado: (2015)

A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their Functions
por: Giebeler, Nives, et al.
Publicado: (2016)

Disintegrin-Integrin Binding for Attachment of Polymer Substrate to the Retina
por: Gonzalez-Calle, Alejandra, et al.
Publicado: (2018)

Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases
por: Dreymueller, D., et al.
Publicado: (2017)

A Disintegrin and Metalloproteinase—Control Elements in Infectious Diseases
por: Aljohmani, Ahmad, et al.
Publicado: (2020)

Benefits of resistance training on body composition and glucose clearance are inhibited by long-term low carbohydrate diet in rats
por: Stotzer, Uliana Sbeguen, et al.
Publicado: (2018)

Snake Venom Metalloproteinases (SVMPs): A structure-function update
por: Olaoba, Olamide Tosin, et al.
Publicado: (2020)

Multimeric Disintegrin Protein Polymer Fusions That Target Tumor Vasculature
por: Janib, Siti M., et al.
Publicado: (2014)

Disintegrins from Snake Venoms and their Applications in Cancer  Research and Therapy
por: Macêdo, Jéssica Kele Arruda, et al.
Publicado: (2015)

A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems
por: Xu, Jiaxi, et al.
Publicado: (2016)

A Disintegrin and Metalloproteases (ADAMs): Activation, Regulation and Mechanisms of Catalysis
por: Maretzky, Thorsten
Publicado: (2021)

Molecular switch in human diseases-disintegrin and metalloproteinases, ADAM17
por: Yang, Guang, et al.
Publicado: (2021)

Effect of type 2 diabetes on A disintegrin and metalloprotease 10
por: Lam, Sum, et al.
Publicado: (2022)

Snake venom disintegrins update: insights about new findings
por: Almeida, Gabriela de Oliveira, et al.
Publicado: (2023)

Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells
por: Hammouda, Manel B., et al.
Publicado: (2016)

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
por: Chalaris, Athena, et al.
Publicado: (2010)

'Future of DIS': Summary
por: Laycock, Paul, et al.
Publicado: (2010)

DIS '95: an overview
por: Altarelli, Guido
Publicado: (1995)

Summary of DIS '98
por: Ellis, John R.
Publicado: (1998)

Jet production in DIS
por: Graudenz, Dirk
Publicado: (1999)

Multiple Scattering in DIS
por: Kowalski, H
Publicado: (2005)

Law and dis/abilities
por: Sagar, Arun
Publicado: (2021)

Diffractive DIS Cross Sections and Parton Distributions
por: Schilling, F.P.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_57tnhksu6fjqhd3o2k7seft3dm