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Hypoxia-induced miR-191-C/EBPβ signaling regulates cell proliferation and apoptosis of fibroblast-like synoviocytes from patients with rheumatoid arthritis

BACKGROUND: Hypoxia plays an important role in the proliferation of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), leading to pathology of RA. This study was conducted to evaluate hypoxia-induced microRNAs (hypoxamiR) in RA-FLS and its role in the function of RA-FLS. METHODS: RA-FLS wer...

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Detalles Bibliográficos
Autores principales: Yu, Shanshan, Lu, Ying, Zong, Ming, Tan, Qi, Fan, Lieying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425666/
https://www.ncbi.nlm.nih.gov/pubmed/30894209
http://dx.doi.org/10.1186/s13075-019-1861-7