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Pragmatic trials: ignoring a mediator and adjusting for confounding
OBJECTIVES: In pragmatic trials, the new treatment is compared with usual care (heterogeneous control arm) that makes the comparison of the new treatment with each treatment within the control arm more difficult. The usual assumption is that we can fully capture the relations between different quant...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425675/ https://www.ncbi.nlm.nih.gov/pubmed/30894221 http://dx.doi.org/10.1186/s13104-019-4188-1 |