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Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma

BACKGROUND: Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated. The main harmful component of LPR is pepsin, which has been shown to induce mucosal inflammation by...

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Detalles Bibliográficos
Autores principales: Tan, Jia-Jie, Wang, Lu, Mo, Ting-Ting, Wang, Jie, Wang, Mei-Gui, Li, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425698/
https://www.ncbi.nlm.nih.gov/pubmed/30936780
http://dx.doi.org/10.1186/s12935-019-0772-7