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Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma
BACKGROUND: Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated. The main harmful component of LPR is pepsin, which has been shown to induce mucosal inflammation by...
Autores principales: | Tan, Jia-Jie, Wang, Lu, Mo, Ting-Ting, Wang, Jie, Wang, Mei-Gui, Li, Xiang-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425698/ https://www.ncbi.nlm.nih.gov/pubmed/30936780 http://dx.doi.org/10.1186/s12935-019-0772-7 |
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