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A Model of Glucocorticoid Receptor Interaction With Coregulators Predicts Transcriptional Regulation of Target Genes

Regulatory factors that control gene transcription in multicellular organisms are assembled in multicomponent complexes by combinatorial interactions. In this context, nuclear receptors provide well-characterized and physiologically relevant systems to study ligand-induced transcription resulting fr...

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Detalles Bibliográficos
Autores principales: Monczor, Federico, Chatzopoulou, Antonia, Zappia, Carlos Daniel, Houtman, René, Meijer, Onno C., Fitzsimons, Carlos P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425864/
https://www.ncbi.nlm.nih.gov/pubmed/30930776
http://dx.doi.org/10.3389/fphar.2019.00214