FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

The transcription factor FOXM1 contributes to cell cycle progression and is significantly upregulated in basal-like breast cancer (BLBC). Despite its importance in normal and cancer cell cycles, we lack a complete understanding of mechanisms that regulate FOXM1. We identified USP21 in an RNAi-based...

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Detalles Bibliográficos
Autores principales: Arceci, Anthony, Bonacci, Thomas, Wang, Xianxi, Stewart, Kyle, Damrauer, Jeffrey S., Hoadley, Katherine A., Emanuele, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
https://www.ncbi.nlm.nih.gov/pubmed/30865895
http://dx.doi.org/10.1016/j.celrep.2019.02.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
https://www.ncbi.nlm.nih.gov/pubmed/30865895
http://dx.doi.org/10.1016/j.celrep.2019.02.054

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