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Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue

Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage. The etiology of dengue-associated thrombocytopenia is multifactorial and includes increased platelet clearance. The...

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Detalles Bibliográficos
Autores principales: Riswari, Silvita Fitri, Tunjungputri, Rahajeng N., Kullaya, Vesla, Garishah, Fadel M., Utari, Gloria S. R., Farhanah, Nur, Overheul, Gijs J., Alisjahbana, Bachti, Gasem, M. Hussein, Urbanus, Rolf T., de Groot, Philip. G., Lefeber, Dirk J., van Rij, Ronald P., van der Ven, Andre, de Mast, Quirijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426266/
https://www.ncbi.nlm.nih.gov/pubmed/30849118
http://dx.doi.org/10.1371/journal.ppat.1007500