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HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice

BACKGROUND: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart, HDACs (histone deacetylases) control remodeling associated processes like hypertrophy, fibrosis, and energy me...

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Detalles Bibliográficos
Autores principales: Scholz, Beatrix, Schulte, Jan Sebastian, Hamer, Sabine, Himmler, Kirsten, Pluteanu, Florentina, Seidl, Matthias Dodo, Stein, Juliane, Wardelmann, Eva, Hammer, Elke, Völker, Uwe, Müller, Frank Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426346/
https://www.ncbi.nlm.nih.gov/pubmed/30879335
http://dx.doi.org/10.1161/CIRCEP.118.007071