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HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice
BACKGROUND: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart, HDACs (histone deacetylases) control remodeling associated processes like hypertrophy, fibrosis, and energy me...
Autores principales: | Scholz, Beatrix, Schulte, Jan Sebastian, Hamer, Sabine, Himmler, Kirsten, Pluteanu, Florentina, Seidl, Matthias Dodo, Stein, Juliane, Wardelmann, Eva, Hammer, Elke, Völker, Uwe, Müller, Frank Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426346/ https://www.ncbi.nlm.nih.gov/pubmed/30879335 http://dx.doi.org/10.1161/CIRCEP.118.007071 |
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