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Donepezil's Effects on Brain Functions of Patients With Alzheimer Disease: A Regional Homogeneity Study Based on Resting-State Functional Magnetic Resonance Imaging

PURPOSE: Donepezil is known to increase cholinergic synaptic transmission in Alzheimer disease (AD), although how it affects cortical brain activity and how it consequently affects brain functions need further clarification. To investigate the therapeutic mechanism of donepezil underlying its effect...

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Detalles Bibliográficos
Autores principales: Cheng, Jianan, Yang, Hua, Zhang, Jiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426347/
https://www.ncbi.nlm.nih.gov/pubmed/30875345
http://dx.doi.org/10.1097/WNF.0000000000000324