Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis

Vascular morphogenesis is the formation of endothelial lumenized networks. Cluster-based vasculogenesis of endothelial progenitor cells (EPCs) has been observed in animal models, but the underlying mechanism is unknown. Here, using O(2)-controllabe hydrogels, we unveil the mechanism by which hypoxia...

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Detalles Bibliográficos
Autores principales: Blatchley, Michael R., Hall, Franklyn, Wang, Songnan, Pruitt, Hawley C., Gerecht, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426463/
https://www.ncbi.nlm.nih.gov/pubmed/30906859
http://dx.doi.org/10.1126/sciadv.aau7518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426463/
https://www.ncbi.nlm.nih.gov/pubmed/30906859
http://dx.doi.org/10.1126/sciadv.aau7518

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