Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines

Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens. We showed, through use of a CRISPR-Cas9 CD40 knockout, that the superantigens toxic shock...

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Detalles Bibliográficos
Autores principales: Schlievert, Patrick M., Cahill, Michael P., Hostager, Bruce S., Brosnahan, Amanda J., Klingelhutz, Aloysius J., Gourronc, Francoise A., Bishop, Gail A., Leung, Donald Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426597/
https://www.ncbi.nlm.nih.gov/pubmed/30890614
http://dx.doi.org/10.1128/mBio.00214-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426597/
https://www.ncbi.nlm.nih.gov/pubmed/30890614
http://dx.doi.org/10.1128/mBio.00214-19

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