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Werner Helicase Control of Human Papillomavirus 16 E1-E2 DNA Replication Is Regulated by SIRT1 Deacetylation

Human papillomaviruses (HPV) are double-stranded DNA viruses causative in a host of human diseases, including several cancers. Following infection, two viral proteins, E1 and E2, activate viral replication in association with cellular factors and stimulate the DNA damage response (DDR) during the re...

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Detalles Bibliográficos
Autores principales: Das, Dipon, Bristol, Molly L., Smith, Nathan W., James, Claire D., Wang, Xu, Pichierri, Pietro, Morgan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426601/
https://www.ncbi.nlm.nih.gov/pubmed/30890607
http://dx.doi.org/10.1128/mBio.00263-19