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Clostridium difficile Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule

Clostridium (Clostridioides) difficile infection (CDI) is associated with dysbiosis. C. difficile has a characteristic propensity to persist and recur 1 to 4 weeks after treatment, but the mechanism is unknown. We hypothesized that C. difficile may persist by manipulating the intestinal microenviron...

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Detalles Bibliográficos
Autores principales: Darkoh, Charles, Plants-Paris, Kimberly, Bishoff, Dayna, DuPont, Herbert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426650/
https://www.ncbi.nlm.nih.gov/pubmed/30944877
http://dx.doi.org/10.1128/mSystems.00346-18