Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response

In eukaryotes, tRNAs are transcribed in the nucleus and exported to the cytosol, where they deliver amino acids to ribosomes for protein translation. This nuclear-cytoplasmic movement was believed to be unidirectional. However, active shuttling of tRNAs, named tRNA retrograde transport, between the...

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Detalles Bibliográficos
Autores principales: Schwenzer, Hagen, Jühling, Frank, Chu, Alexander, Pallett, Laura J., Baumert, Thomas F., Maini, Mala, Fassati, Ariberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426654/
https://www.ncbi.nlm.nih.gov/pubmed/30893612
http://dx.doi.org/10.1016/j.celrep.2019.02.077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426654/
https://www.ncbi.nlm.nih.gov/pubmed/30893612
http://dx.doi.org/10.1016/j.celrep.2019.02.077

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