Tetrafunctional Block Copolymers Promote Lung Gene Transfer in Newborn Piglets

Tetrafunctional block copolymers are molecules capable of complexing DNA. Although ineffective in vitro, studies in mice have shown that the tetrafunctional block copolymer 704 is a more efficient lung gene transfer agent than the cationic liposome GL67A, previously used in a phase II clinical trial...

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Detalles Bibliográficos
Autores principales: Caballero, Ignacio, Riou, Mickaël, Hacquin, Océane, Chevaleyre, Claire, Barc, Céline, Pezant, Jérémy, Pinard, Anne, Fassy, Julien, Rezzonico, Roger, Mari, Bernard, Heuzé-Vourc’h, Nathalie, Pitard, Bruno, Vassaux, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426709/
https://www.ncbi.nlm.nih.gov/pubmed/30897407
http://dx.doi.org/10.1016/j.omtn.2019.02.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426709/
https://www.ncbi.nlm.nih.gov/pubmed/30897407
http://dx.doi.org/10.1016/j.omtn.2019.02.016

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