Tau drives translational selectivity by interacting with ribosomal proteins

There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo. Here, we investigated the consequences of tau interactions with ribosomes in transgenic mice,...

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Detalles Bibliográficos
Autores principales: Koren, Shon A., Hamm, Matthew J., Meier, Shelby E., Weiss, Blaine E., Nation, Grant K., Chishti, Emad A., Arango, Juan Pablo, Chen, Jing, Zhu, Haining, Blalock, Eric M., Abisambra, Jose F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426815/
https://www.ncbi.nlm.nih.gov/pubmed/30759285
http://dx.doi.org/10.1007/s00401-019-01970-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426815/
https://www.ncbi.nlm.nih.gov/pubmed/30759285
http://dx.doi.org/10.1007/s00401-019-01970-9

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