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Tau drives translational selectivity by interacting with ribosomal proteins
There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo. Here, we investigated the consequences of tau interactions with ribosomes in transgenic mice,...
Autores principales: | Koren, Shon A., Hamm, Matthew J., Meier, Shelby E., Weiss, Blaine E., Nation, Grant K., Chishti, Emad A., Arango, Juan Pablo, Chen, Jing, Zhu, Haining, Blalock, Eric M., Abisambra, Jose F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426815/ https://www.ncbi.nlm.nih.gov/pubmed/30759285 http://dx.doi.org/10.1007/s00401-019-01970-9 |
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