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Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling

Development of lymphatics takes place during embryogenesis, wound healing, inflammation, and cancer. We previously showed that Wnt5a is an essential regulator of lymphatic development in the dermis of mice, however, the mechanisms of action remained unclear. Here, whole-mount immunostaining shows th...

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Detalles Bibliográficos
Autores principales: Lutze, Grit, Haarmann, Anna, Demanou Toukam, Jules A., Buttler, Kerstin, Wilting, Jörg, Becker, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426866/
https://www.ncbi.nlm.nih.gov/pubmed/30894622
http://dx.doi.org/10.1038/s41598-019-41299-7