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Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling
Development of lymphatics takes place during embryogenesis, wound healing, inflammation, and cancer. We previously showed that Wnt5a is an essential regulator of lymphatic development in the dermis of mice, however, the mechanisms of action remained unclear. Here, whole-mount immunostaining shows th...
Autores principales: | Lutze, Grit, Haarmann, Anna, Demanou Toukam, Jules A., Buttler, Kerstin, Wilting, Jörg, Becker, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426866/ https://www.ncbi.nlm.nih.gov/pubmed/30894622 http://dx.doi.org/10.1038/s41598-019-41299-7 |
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