Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides

Interleukin-1β (IL-1β) is a major cytokine that initiates and enhances inflammatory responses. Excessive IL-1β production is a characteristic of most chronic inflammatory diseases, including atherosclerosis, type 2 diabetes, and obesity, which affect a large proportion of the global population. The...

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Detalles Bibliográficos
Autores principales: Pal, Arumay, Neo, Kurt, Rajamani, Lakshminarayanan, Ferrer, Fernando Jose, Lane, David P., Verma, Chandra S., Mortellaro, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426897/
https://www.ncbi.nlm.nih.gov/pubmed/30894604
http://dx.doi.org/10.1038/s41598-019-41211-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426897/
https://www.ncbi.nlm.nih.gov/pubmed/30894604
http://dx.doi.org/10.1038/s41598-019-41211-3

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