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Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
Interleukin-1β (IL-1β) is a major cytokine that initiates and enhances inflammatory responses. Excessive IL-1β production is a characteristic of most chronic inflammatory diseases, including atherosclerosis, type 2 diabetes, and obesity, which affect a large proportion of the global population. The...
Autores principales: | Pal, Arumay, Neo, Kurt, Rajamani, Lakshminarayanan, Ferrer, Fernando Jose, Lane, David P., Verma, Chandra S., Mortellaro, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426897/ https://www.ncbi.nlm.nih.gov/pubmed/30894604 http://dx.doi.org/10.1038/s41598-019-41211-3 |
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