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White matter microstructural abnormalities and default network degeneration are associated with early memory deficit in Alzheimer’s disease continuum

Instead of assuming a constant relationship between brain abnormalities and memory impairment, we aimed to examine the stage-dependent contributions of multimodal brain structural and functional deterioration to memory impairment in the Alzheimer’s disease (AD) continuum. We assessed grey matter vol...

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Detalles Bibliográficos
Autores principales: Ji, Fang, Pasternak, Ofer, Ng, Kwun Kei, Chong, Joanna Su Xian, Liu, Siwei, Zhang, Liwen, Shim, Hee Youn, Loke, Yng Miin, Tan, Boon Yeow, Venketasubramanian, Narayanaswamy, Chen, Christopher Li-Hsian, Zhou, Juan Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426923/
https://www.ncbi.nlm.nih.gov/pubmed/30894627
http://dx.doi.org/10.1038/s41598-019-41363-2