Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer

ABCB1 encodes Multidrug Resistance protein (MDR1), an ATP-binding cassette member involved in the cellular efflux of chemotherapeutic drugs. Here we report that ovarian and breast samples from chemotherapy treated patients are positive for multiple transcriptional fusions involving ABCB1, placing it...

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Detalles Bibliográficos
Autores principales: Christie, Elizabeth L., Pattnaik, Swetansu, Beach, Jessica, Copeland, Anthony, Rashoo, Nineveh, Fereday, Sian, Hendley, Joy, Alsop, Kathryn, Brady, Samuel L., Lamb, Greg, Pandey, Ahwan, deFazio, Anna, Thorne, Heather, Bild, Andrea, Bowtell, David D. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426934/
https://www.ncbi.nlm.nih.gov/pubmed/30894541
http://dx.doi.org/10.1038/s41467-019-09312-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426934/
https://www.ncbi.nlm.nih.gov/pubmed/30894541
http://dx.doi.org/10.1038/s41467-019-09312-9

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