Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability

Mechanisms underlying the generation of induced pluripotent stem cells (iPSC) and keeping iPSC stability remain to be further defined. Accumulated evidences showed that iPSC reprogramming may be controlled by the cell-division-rate-dependent model. Here we reported effects of absence of mouse p27 or...

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Detalles Bibliográficos
Autores principales: Zhan, Zhiyan, Song, Lili, Zhang, Weiwei, Gu, Haihui, Cheng, Haizi, Zhang, Yingwen, Yang, Yi, Ji, Guangzhen, Feng, Haizhong, Cheng, Tao, Li, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426969/
https://www.ncbi.nlm.nih.gov/pubmed/30894510
http://dx.doi.org/10.1038/s41419-019-1502-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426969/
https://www.ncbi.nlm.nih.gov/pubmed/30894510
http://dx.doi.org/10.1038/s41419-019-1502-8

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