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Comparison of human isogeneic Wharton’s jelly MSCs and iPSC-derived MSCs reveals differentiation-dependent metabolic responses to IFNG stimulation

Variability among donors, non-standardized methods for isolation, and characterization contribute to mesenchymal stem/stromal cell (MSC) heterogeneity. Induced pluripotent stem cell (iPSCs)-derived MSCs would circumvent many of current issues and enable large-scale production of standardized cellula...

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Detalles Bibliográficos
Autores principales: Devito, Liani, Klontzas, Michail E., Cvoro, Aleksandra, Galleu, Antonio, Simon, Marisa, Hobbs, Carl, Dazzi, Francesco, Mantalaris, Athanasios, Khalaf, Yacoub, Ilic, Dusko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426992/
https://www.ncbi.nlm.nih.gov/pubmed/30894508
http://dx.doi.org/10.1038/s41419-019-1498-0