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Epitope mapping of diverse influenza Hemagglutinin drug candidates using HDX-MS
Epitope characterization is critical for elucidating the mechanism of action of drug candidates. However, traditional high-resolution epitope mapping techniques are not well suited for screening numerous drug candidates recognizing a similar target. Here, we use Hydrogen-Deuterium Exchange Mass Spec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427009/ https://www.ncbi.nlm.nih.gov/pubmed/30894620 http://dx.doi.org/10.1038/s41598-019-41179-0 |