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Loss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signals

Crystals can trigger a wide range of kidney injuries that may link to the development of kidney stones. Infiltrating macrophages may influence hyperoxaluria-induced intrarenal calcium oxalate (CaOx) crystals deposition, yet their linkage to sex hormones remains unclear. Here we demonstrated that sup...

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Detalles Bibliográficos
Autores principales: Zhu, Wei, Zhao, Zhijian, Chou, Fuju, Zuo, Li, Liu, Tongzu, Yeh, Shuyuan, Bushinsky, David, Zeng, Guohua, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427030/
https://www.ncbi.nlm.nih.gov/pubmed/30894518
http://dx.doi.org/10.1038/s41419-019-1358-y