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Calcium electroporation and electrochemotherapy for cancer treatment: Importance of cell membrane composition investigated by lipidomics, calorimetry and in vitro efficacy

Calcium electroporation is a novel anti-cancer treatment investigated in clinical trials. We explored cell sensitivity to calcium electroporation and electroporation with bleomycin, using viability assays at different time and temperature points, as well as heat calorimetry, lipidomics, and flow cyt...

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Detalles Bibliográficos
Autores principales: Hoejholt, K. L., Mužić, T., Jensen, S. D., Dalgaard, L. T., Bilgin, M., Nylandsted, J., Heimburg, T., Frandsen, S. K., Gehl, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427041/
https://www.ncbi.nlm.nih.gov/pubmed/30894594
http://dx.doi.org/10.1038/s41598-019-41188-z