Cargando…
NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration
NCOA4 (Nuclear receptor coactivator 4) mediates the selective autophagic degradation of ferritin, the cellular cytosolic iron storage complex, thereby playing a critical role in intracellular and systemic iron homeostasis. Disruptions in iron homeostasis and autophagy are observed in several neurode...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427834/ https://www.ncbi.nlm.nih.gov/pubmed/30930742 http://dx.doi.org/10.3389/fnins.2019.00238 |