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NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration

NCOA4 (Nuclear receptor coactivator 4) mediates the selective autophagic degradation of ferritin, the cellular cytosolic iron storage complex, thereby playing a critical role in intracellular and systemic iron homeostasis. Disruptions in iron homeostasis and autophagy are observed in several neurode...

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Detalles Bibliográficos
Autores principales:	Quiles del Rey, Maria, Mancias, Joseph D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427834/ https://www.ncbi.nlm.nih.gov/pubmed/30930742 http://dx.doi.org/10.3389/fnins.2019.00238

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