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Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line
BACKGROUND: Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen is based on carboplatin (CBDCA). However, CBDCA resistance is the main obstacle to a better prognosis. An in vitro drug-resistant cell model would help in the understa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427839/ https://www.ncbi.nlm.nih.gov/pubmed/30894224 http://dx.doi.org/10.1186/s40659-019-0220-0 |