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Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line

BACKGROUND: Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen is based on carboplatin (CBDCA). However, CBDCA resistance is the main obstacle to a better prognosis. An in vitro drug-resistant cell model would help in the understa...

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Detalles Bibliográficos
Autores principales: Viscarra, Tamara, Buchegger, Kurt, Jofre, Ignacio, Riquelme, Ismael, Zanella, Louise, Abanto, Michel, Parker, Alyssa C., Piccolo, Stephen R., Roa, Juan Carlos, Ili, Carmen, Brebi, Priscilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427839/
https://www.ncbi.nlm.nih.gov/pubmed/30894224
http://dx.doi.org/10.1186/s40659-019-0220-0