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Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep–wake cycle

BACKGROUND: Previous data show that serotonin 2C (5-HT(2C)) and cannabinoid 1 (CB(1)) receptors have a role in the modulation of sleep–wake cycle. Namely, antagonists on these receptors promoted wakefulness and inhibited rapid eye movement sleep (REMS) in rodents. The interaction of these receptors...

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Detalles Bibliográficos
Autores principales: Bogáthy, Emese, Papp, Noémi, Tóthfalusi, Laszló, Vas, Szilvia, Bagdy, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427841/
https://www.ncbi.nlm.nih.gov/pubmed/30894126
http://dx.doi.org/10.1186/s12868-019-0495-7