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Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep–wake cycle
BACKGROUND: Previous data show that serotonin 2C (5-HT(2C)) and cannabinoid 1 (CB(1)) receptors have a role in the modulation of sleep–wake cycle. Namely, antagonists on these receptors promoted wakefulness and inhibited rapid eye movement sleep (REMS) in rodents. The interaction of these receptors...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427841/ https://www.ncbi.nlm.nih.gov/pubmed/30894126 http://dx.doi.org/10.1186/s12868-019-0495-7 |