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Modulation of acetate utilization in Komagataella phaffii by metabolic engineering of tolerance and metabolism

BACKGROUND: Acetate, an economical industrial chemical, which is also the precursor of acetyl-CoA, could serve as an alternative substrate for biomanufacturing. This nontraditional substrate can be widely produced from syngas via hydrolysis or pyrolysis of the cellulosic biomass, chemical or microbi...

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Detalles Bibliográficos
Autores principales: Xu, Qin, Bai, Chenxiao, Liu, Yiqi, Song, Lili, Tian, Lin, Yan, Yunfeng, Zhou, Jinfeng, Zhou, Xiangshan, Zhang, Yuanxing, Cai, Menghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427870/
https://www.ncbi.nlm.nih.gov/pubmed/30936941
http://dx.doi.org/10.1186/s13068-019-1404-0