Cargando…

Modulation of acetate utilization in Komagataella phaffii by metabolic engineering of tolerance and metabolism

BACKGROUND: Acetate, an economical industrial chemical, which is also the precursor of acetyl-CoA, could serve as an alternative substrate for biomanufacturing. This nontraditional substrate can be widely produced from syngas via hydrolysis or pyrolysis of the cellulosic biomass, chemical or microbi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Qin, Bai, Chenxiao, Liu, Yiqi, Song, Lili, Tian, Lin, Yan, Yunfeng, Zhou, Jinfeng, Zhou, Xiangshan, Zhang, Yuanxing, Cai, Menghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427870/ https://www.ncbi.nlm.nih.gov/pubmed/30936941 http://dx.doi.org/10.1186/s13068-019-1404-0

Ejemplares similares

Metabolic modeling to identify engineering targets for Komagataella phaffii: The effect of biomass composition on gene target identification
por: Cankorur‐Cetinkaya, Ayca, et al.
Publicado: (2017)

What makes Komagataella phaffii non-conventional?
por: Ata, Özge, et al.
Publicado: (2021)

Advances in Cell Engineering of the Komagataella phaffii Platform for Recombinant Protein Production
por: Bustos, Cristina, et al.
Publicado: (2022)

Role of Dissimilative Pathway of Komagataella phaffii (Pichia pastoris): Formaldehyde Toxicity and Energy Metabolism
por: Berrios, Julio, et al.
Publicado: (2022)

Identification and characterization of the Komagataella phaffii mating pheromone genes
por: Heistinger, Lina, et al.
Publicado: (2018)

A subcellular proteome atlas of the yeast Komagataella phaffii
por: Valli, Minoska, et al.
Publicado: (2020)

Komagataella phaffii as Emerging Model Organism in Fundamental Research
por: Bernauer, Lukas, et al.
Publicado: (2021)

Effect of Methionine on Gene Expression in Komagataella phaffii Cells
por: Ianshina, Tatiana, et al.
Publicado: (2023)

Industrial Production of Proteins with Pichia pastoris—Komagataella phaffii
por: Barone, Giovanni Davide, et al.
Publicado: (2023)

Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family
por: De, Sonakshi, et al.
Publicado: (2020)

Histidine is essential for growth of Komagataella phaffii cultured in YPA medium
por: Gupta, Aditi, et al.
Publicado: (2022)

Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
por: Albacar, Marcel, et al.
Publicado: (2023)

Alternative PCR-Based Approaches for Generation of Komagataella phaffii Strains
por: Makeeva, Anastasiya, et al.
Publicado: (2023)

Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid
por: Àvila-Cabré, Sílvia, et al.
Publicado: (2023)

Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii
por: Barbay, Diane, et al.
Publicado: (2021)

Coordinate regulation of methanol utilization pathway genes of Komagataella phaffii by transcription factors and chromatin modifiers
por: Gupta, Aditi, et al.
Publicado: (2022)

Evaluation of reference genes for transcript analyses in Komagataella phaffii (Pichia pastoris)
por: Besleaga, Mihail, et al.
Publicado: (2023)

Correction: Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
por: Albacar, Marcel, et al.
Publicado: (2023)

Use of an on/off tetracycline riboswitch to control protein production in Komagataella phaffii
por: Vieira, Igor Patrick Vasconcelos, et al.
Publicado: (2023)

The oxygen-tolerant reductive glycine pathway assimilates methanol, formate and CO(2) in the yeast Komagataella phaffii
por: Mitic, Bernd M., et al.
Publicado: (2023)

Systematic sequence engineering enhances the induction strength of the glucose-regulated GTH1 promoter of Komagataella phaffii
por: Flores-Villegas, Mirelle, et al.
Publicado: (2023)

Process development for the continuous production of heterologous proteins by the industrial yeast, Komagataella phaffii
por: Cankorur‐Cetinkaya, Ayca, et al.
Publicado: (2018)

Multicopy plasmid integration in Komagataella phaffii mediated by a defective auxotrophic marker
por: Betancur, Maritza Ocampo, et al.
Publicado: (2017)

Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii
por: Alva, Troy R., et al.
Publicado: (2021)

Transcriptome Analysis Unveils the Effects of Proline on Gene Expression in the Yeast Komagataella phaffii
por: Rumyantsev, Andrey, et al.
Publicado: (2021)

Regulation of Peroxisome Homeostasis by Post-Translational Modification in the Methylotrophic Yeast Komagataella phaffii
por: Ohsawa, Shin, et al.
Publicado: (2022)

Heterologous Expression of Extracellular Proteinase pAsPs of Aspergillus pseudotamarii in Komagataella phaffii
por: Zadorozhny, Andrey Valentinovich, et al.
Publicado: (2022)

Engineering the expression system for Komagataella phaffii (Pichia pastoris): an attempt to develop a methanol-free expression system
por: Takagi, Shinobu, et al.
Publicado: (2019)

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii
por: Dalvie, Neil C., et al.
Publicado: (2021)

Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii
por: Dalvie, Neil C., et al.
Publicado: (2021)

A streamlined strain engineering workflow with genome-wide screening detects enhanced protein secretion in Komagataella phaffii
por: Ito, Yoichiro, et al.
Publicado: (2022)

Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation
por: Heistinger, Lina, et al.
Publicado: (2017)

L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
por: Freitas, Marcela, et al.
Publicado: (2022)

Heterologous Expression of Xylanase xAor from Aspergillus oryzae in Komagataella phaffii T07
por: Zadorozhny, Andrey Valentinovich, et al.
Publicado: (2022)

Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications
por: Swichkow, Chantle Reiko, et al.
Publicado: (2022)

Effect of Pyruvate Decarboxylase Knockout on Product Distribution Using Pichia pastoris (Komagataella phaffii) Engineered for Lactic Acid Production
por: Melo, Nadiele T. M., et al.
Publicado: (2018)

Evaluation of Product Distribution in Chemostat and Batch Fermentation in Lactic Acid-Producing Komagataella phaffii Strains Utilizing Glycerol as Substrate
por: Tamires Moreira Melo, Nadielle, et al.
Publicado: (2020)

Centromeres of the Yeast Komagataella phaffii (Pichia pastoris) Have a Simple Inverted-Repeat Structure
por: Coughlan, Aisling Y., et al.
Publicado: (2016)

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
por: Ata, Özge, et al.
Publicado: (2018)

Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)
por: Braun-Galleani, Stephanie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_djrob7a2oep3smpifcu9i79fc0