Nanomedicine-Assisted Combination Therapy of NSCLC: New Platinum-Based Anticancer Drug Synergizes the Therapeutic Efficacy of Ganetespib

Purpose: K-RAS is the most common mutated oncogene associated with Non-Small-Cell Lung Cancer (NSCLC). So far, there are no promising chemotherapies for the direct inhibition of K-RAS, and considered to be undruggable. In this work, we have introduced a new platinum-based cyanoximate complex, Pt(MCO...

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Detalles Bibliográficos
Autores principales: Kallu, Jyothi, Banerjee, Tuhina, Sulthana, Shoukath, Darji, Saloni, Higginbotham, Ryan, Fletcher, Christina, Gerasimchuk, Nikolay N., Santra, Santimukul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427934/
https://www.ncbi.nlm.nih.gov/pubmed/30899640
http://dx.doi.org/10.7150/ntno.28468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427934/
https://www.ncbi.nlm.nih.gov/pubmed/30899640
http://dx.doi.org/10.7150/ntno.28468

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