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N1-Methyladenosine detection with CRISPR-Cas13a/C2c2
Recent studies suggested that the widespread presence of N1-methyladenosine (m(1)A) plays a very important role in environmental stress, ribosome biogenesis and antibiotic resistance. The RNA-guided, RNA-targeting CRISPR Cas13a exhibits a “collateral effect” of promiscuous RNase activity upon target...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427938/ https://www.ncbi.nlm.nih.gov/pubmed/30996876 http://dx.doi.org/10.1039/c8sc03408g |