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N1-Methyladenosine detection with CRISPR-Cas13a/C2c2

Recent studies suggested that the widespread presence of N1-methyladenosine (m(1)A) plays a very important role in environmental stress, ribosome biogenesis and antibiotic resistance. The RNA-guided, RNA-targeting CRISPR Cas13a exhibits a “collateral effect” of promiscuous RNase activity upon target...

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Detalles Bibliográficos
Autores principales:	Chen, Yi, Yang, Shixi, Peng, Shuang, Li, Wei, Wu, Fan, Yao, Qian, Wang, Fang, Weng, Xiaocheng, Zhou, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427938/ https://www.ncbi.nlm.nih.gov/pubmed/30996876 http://dx.doi.org/10.1039/c8sc03408g

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