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Lipid-independent control of endothelial and neuronal TRPC3 channels by light

Lipid-gated TRPC channels are highly expressed in cardiovascular and neuronal tissues. Exerting precise pharmacological control over their activity in native cells is expected to serve as a basis for the development of novel therapies. Here we report on a new photopharmacological tool that enables m...

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Detalles Bibliográficos
Autores principales: Tiapko, Oleksandra, Shrestha, Niroj, Lindinger, Sonja, Guedes de la Cruz, Gema, Graziani, Annarita, Klec, Christiane, Butorac, Carmen, Graier, Wolfgang. F., Kubista, Helmut, Freichel, Marc, Birnbaumer, Lutz, Romanin, Christoph, Glasnov, Toma, Groschner, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427946/
https://www.ncbi.nlm.nih.gov/pubmed/30997005
http://dx.doi.org/10.1039/c8sc05536j