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Sex-regulated gene dosage effect of PPARα on synaptic plasticity

Mechanisms driving cognitive improvements following nuclear receptor activation are poorly understood. The peroxisome proliferator–activated nuclear receptor alpha (PPARα) forms heterodimers with the nuclear retinoid X receptor (RXR). We report that PPARα mediates the improvement of hippocampal syna...

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Detalles Bibliográficos
Autores principales: Pierrot, Nathalie, Ris, Laurence, Stancu, Ilie-Cosmin, Doshina, Anna, Ribeiro, Floriane, Tyteca, Donatienne, Baugé, Eric, Lalloyer, Fanny, Malong, Liza, Schakman, Olivier, Leroy, Karelle, Kienlen-Campard, Pascal, Gailly, Philippe, Brion, Jean-Pierre, Dewachter, Ilse, Staels, Bart, Octave, Jean-Noël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427998/
https://www.ncbi.nlm.nih.gov/pubmed/30894406
http://dx.doi.org/10.26508/lsa.201800262