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Sex-regulated gene dosage effect of PPARα on synaptic plasticity
Mechanisms driving cognitive improvements following nuclear receptor activation are poorly understood. The peroxisome proliferator–activated nuclear receptor alpha (PPARα) forms heterodimers with the nuclear retinoid X receptor (RXR). We report that PPARα mediates the improvement of hippocampal syna...
Autores principales: | Pierrot, Nathalie, Ris, Laurence, Stancu, Ilie-Cosmin, Doshina, Anna, Ribeiro, Floriane, Tyteca, Donatienne, Baugé, Eric, Lalloyer, Fanny, Malong, Liza, Schakman, Olivier, Leroy, Karelle, Kienlen-Campard, Pascal, Gailly, Philippe, Brion, Jean-Pierre, Dewachter, Ilse, Staels, Bart, Octave, Jean-Noël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427998/ https://www.ncbi.nlm.nih.gov/pubmed/30894406 http://dx.doi.org/10.26508/lsa.201800262 |
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