Delayed γH2AX foci disappearance in mammary epithelial cells from aged women reveals an age-associated DNA repair defect

Aging is a degenerative process in which genome instability plays a crucial role. To gain insight into the link between organismal aging and DNA repair capacity, we analyzed DNA double-strand break (DSB) resolution efficiency in human mammary epithelial cells from 12 healthy donors of young and old...

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Detalles Bibliográficos
Autores principales: Anglada, Teresa, Repullés, Joan, Espinal, Anna, LaBarge, Mark A, Stampfer, Martha R, Genescà, Anna, Martín, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428106/
https://www.ncbi.nlm.nih.gov/pubmed/30875333
http://dx.doi.org/10.18632/aging.101849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428106/
https://www.ncbi.nlm.nih.gov/pubmed/30875333
http://dx.doi.org/10.18632/aging.101849

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