LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation

The Mycobacterium tuberculosis kinase PknB is essential for growth and survival of the pathogen in vitro and in vivo. Here we report the results of our efforts to elucidate the mechanism of regulation of PknB activity. The specific residues in the PknB extracytoplasmic domain that are essential for...

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Detalles Bibliográficos
Autores principales: Kaur, Prabhjot, Rausch, Marvin, Malakar, Basanti, Watson, Uchenna, Damle, Nikhil P., Chawla, Yogesh, Srinivasan, Sandhya, Sharma, Kanika, Schneider, Tanja, Jhingan, Gagan Deep, Saini, Deepak, Mohanty, Debasisa, Grein, Fabian, Nandicoori, Vinay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428115/
https://www.ncbi.nlm.nih.gov/pubmed/30874556
http://dx.doi.org/10.1038/s41467-019-09223-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428115/
https://www.ncbi.nlm.nih.gov/pubmed/30874556
http://dx.doi.org/10.1038/s41467-019-09223-9

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